Cell Cycle Under Control of Glycosaminoglycans?!

Cell cycle control of BRCA2.

Identifying the conditions and kinetics of the induction of BRCA2 gene expression may implicate roles for the function of the tumor suppressor gene. In this study, expression of BRCA2 mRNA is shown to be regulated by the cell cycle and associated with proliferation in normal and tumor-derived breast epithelial cells. Cells arrested in G(0) or early G1 contained low levels of BRCA2 mRNA. After r...

Cell Cycle: Principles of Control

tion at the end of each case. For students desiring a more in-depth review, the analysis section of each case provides a great and more detailed overview. An extra index organized by disorder name in the back also allows the reader to focus on particular aspects of internal medicine. Details such as this make it obvious that the authors have tried to cater to the varying needs of their readers,...

Optimal Battery Control Under Cycle Aging Mechanisms

We study the optimal control of battery energy storage under a general “pay-for-performance” setup such as providing frequency regulation and renewable integration. Batteries need to carefully balance the trade-off between following to the instruction signals and their degradation costs in realtime. Existing battery control strategies either do not consider the uncertainty of future signals, or...

Syngamy and Cell Cycle Control

Adenovirus and cell cycle control.

Adenovirus infection of quiescent cells induces transition from G0 or G1 into the S phase of the cell cycle and allows cellular proliferation. This is beneficial for the virus since cells in S phase provide optimal conditions for viral replication. Adenovirus E1A, E1B and E4 gene products contribute to cell cycle deregulation. E1A proteins inactivate the pRb checkpoint, allowing the E2F transcr...